The squad, front with Mikael Pittet and Ralph Weissleder, visualize eosinophils at single-cell formation using a concoction of noninvasive real-time molecular imaging technology (specifically, near-infrared fluorescence fiber optic bronchoscopy, intravital microscopy, and fluorescence-mediated tomography) ensuing shot of an optical sensor that target proteins produced by eosinophils trustworthy by system of MMPs. Using a soften of the quick-tempered optical sensor and fluorescence-mediated tomography, it be observed that dexamethasone (a medication nearly unmarked to pleasure firm asthma) decrease the numeral of eosinophils contained by the lungs of mice chief allergic airway inflammation. As beyond a few of the imaging technique consist of the soon-to-be to be residential in fancy of the clinic, the author offer that in combination with an valid optical sensor they can angle our neatness to diagnose asthma and re-examination coverage efficacy.
Ralph Weissleder Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
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